Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_014795.4

p.S424fs

c.1270_1271fs

Surrounding Variants

2 papers

NM_014795.4

p.P425L

c.1274C>T

1 paper

NM_014795.4

p.S424_P425delFs

c.1270_1273del4

1 paper

NM_014795.4

p.T423_P425del0

c.1268_1273del6

2 papers

NM_014795.4

p.L426I

c.1276T>A

5 papers

NM_014795.4

p.L426*

c.1277T>G

5 papers

NM_014795.4

p.L426*

c.1277T>A

1 paper

NM_014795.4

p.G421R

c.1261G>C

1 paper

NM_014795.4

p.G421R

c.1261G>A

4 papers

NM_014795.4

p.L426delFs

c.1278delT

2 papers

NM_014795.4

p.G427fs

c.1279_1280fs

1 paper

NM_014795.4

p.G421fs

c.1261_1262fs

1 paper

NM_014795.4

p.L420R

c.1259T>G