Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014795.4

p.L369delFs

c.1106delA

Surrounding Variants

7 papers

NM_014795.4

p.L369*

c.1106T>G

7 papers

NM_014795.4

p.L369*

c.1106T>A

3 papers

NM_014795.4

p.Q368*

c.1102C>T

2 papers

NM_014795.4

p.L369_K372Fs

c.1106_1115delinsAGFs

1 paper

NM_014795.4

p.K372fs

c.1114_1115fs

1 paper

NM_014795.4

p.K372delFs

c.1115delT

1 paper

NM_014795.4

p.L373M

c.1117T>A

2 papers

NM_014795.4

p.L373fs

c.1117_1118fs

1 paper

NM_014795.4

p.L373delFs

c.1118delA

1 paper

NM_014795.4

p.A365fs

c.1093_1094fs

3 papers

NM_014795.4

p.E374*

c.1120G>T

1 paper

NM_014795.4

p.S364insFs

c.1091_1092dupCA