Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_014795.4

p.Y232*

c.696C>A

Surrounding Variants

10 papers

NM_014795.4

p.Y232*

c.696C>G

3 papers

NM_014795.4

p.Y232fs

c.694_695fs

4 papers

NM_014795.4

p.K231insFs

c.691dupA

1 paper

NM_014795.4

p.H234D

c.700C>G

1 paper

NM_014795.4

p.H234N

c.700C>A

1 paper

NM_014795.4

p.K231fs

c.691_692fs

1 paper

NM_014795.4

p.I230insFs

c.690dupC

1 paper

NM_014795.4

p.E235K

c.703G>A

1 paper

NM_014795.4

p.E235fs

c.703_704fs

1 paper

NM_014795.4

p.K236fs

c.706_707fs

1 paper

NM_014795.4

p.E235_K236delFs

c.705_706delTC

1 paper

NM_014795.4

p.E238*

c.712G>T