Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014795.4

p.G219delFs

c.656delC

Surrounding Variants

1 paper

NM_014795.4

p.R218insFs

c.653dupG

4 papers

NM_014795.4

p.G219fs

c.655_656fs

5 papers

NM_014795.4

p.R218_G219insFs

c.654_655ins4

2 papers

NM_014795.4

p.Y220*

c.660C>G

2 papers

NM_014795.4

p.Y220*

c.660C>A

2 papers

NM_014795.4

p.Y215_Y220delFs

c.643_659del17

2 papers

NM_014795.4

p.D217delFs

c.651delG

1 paper

NM_014795.4

p.R218fs

c.652_653fs

1 paper

NM_014795.4

p.K221T

c.662A>C

1 paper

NM_014795.4

p.R222C

c.664C>T

2 papers

NM_014795.4

p.C216*

c.648C>A

3 papers

NM_014795.4

p.C216delFs

c.647delC