Varaico: Literature-Extracted Genetic Variants

ZEB2

494 papers

RefSeq Summary

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that...

Pfam Domains

zf-Di19aa 209–269UCSCDrought induced 19 protein (Di19), zinc-binding

zf-C2H2aa 282–304UCSCZinc finger, C2H2 type

zf-C2H2aa 310–331UCSCZinc finger, C2H2 type

zf-C2H2aa 999–1021UCSCZinc finger, C2H2 type

zf-C2H2aa 1055–1076UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger E-box binding homeobox 2

HGNC Previous Symbol

ZFHX1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014795.4

p.Y215C

c.644A>G

Surrounding Variants

1 paper

NM_014795.4

p.Y215Y

c.645C>T

1 paper

NM_014795.4

p.Y215fs

c.643_644fs

3 papers

NM_014795.4

p.C216fs

c.646_647fs

2 papers

NM_014795.4

p.C216insFs

c.646dupT

3 papers

NM_014795.4

p.T212_C213insFs

c.635_638dup4

1 paper

NM_014795.4

p.P200_P214insFs

c.600_640dup41

2 papers

NM_014795.4

p.C216*

c.648C>A

3 papers

NM_014795.4

p.C216delFs

c.647delC

3 papers

NM_014795.4

p.P214fs

c.640_641fs

1 paper

NM_014795.4

p.R218fs

c.652_653fs

2 papers

NM_014795.4

p.D217delFs

c.651delG

5 papers

NM_014795.4

p.R218_G219insFs

c.654_655ins4