Varaico: Literature-Extracted Genetic Variants

ZFAT

89 papers

RefSeq Summary

This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyro...

Pfam Domains

zf-C2H2aa 259–281UCSCZinc finger, C2H2 type

zf-H2C2_5aa 287–311UCSCC2H2-type zinc-finger domain

zf-C2H2aa 897–919UCSCZinc finger, C2H2 type

zf-C2H2aa 925–947UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger and AT-hook domain containing

HGNC Previous Symbols

ZNF406; ZFAT1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_020863.4

p.R166W

c.496C>T

NM_001029939.4

p.R154W

c.460C>T

Surrounding Variants

1 paper

NM_001029939.4

p.R160T

c.479G>C

1 paper

NM_020863.4

p.R172S

c.516A>T

1 paper

NM_020863.4

p.R172S

c.516A>C

1 paper

NM_020863.4

p.A195E

c.584C>A

1 paper

NM_020863.4

p.A209V

c.626C>T

1 paper

NM_020863.4

p.P223L

c.668C>T

1 paper

NM_020863.4

p.S235L

c.704C>T

1 paper

NM_020863.4

p.Y254H

c.760T>C

1 paper

NM_020863.4

p.R262S

c.786G>T

1 paper

NM_020863.4

p.R357C

c.1069C>T

1 paper

NM_020863.4

p.C359C

c.1077C>T

1 paper

NM_020863.4

p.T395M

c.1184C>T