Varaico: Literature-Extracted Genetic Variants

ZNF408

129 papers

RefSeq Summary

The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein...

Pfam Domains

PRDM2_PRaa 61–179UCSCPR domain zinc finger protein 2, PR domain

zf-C2H2aa 381–403UCSCZinc finger, C2H2 type

zf-C2H2aa 409–431UCSCZinc finger, C2H2 type

zf-C2H2aa 437–459UCSCZinc finger, C2H2 type

zf-C2H2aa 468–490UCSCZinc finger, C2H2 type

zf-C2H2aa 496–518UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger protein 408

HGNC Alias Symbols

FLJ12827; PRDM17

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024741.3

p.S126T

c.377G>C

Surrounding Variants

6 papers

NM_024741.3

p.S126N

c.377G>A

NM_001184751.2

p.S118N

c.353G>A

1 paper

NM_024741.3

p.Q125Q

c.375G>A

1 paper

NM_024741.3

p.A122T

c.364G>A

3 papers

NM_024741.3

p.A122fs

c.364_365fs

2 papers

NM_024741.3

p.C121_A122delFs

c.363_364delTG

1 paper

NM_024741.3

p.G118E

c.353G>A

2 papers

NM_024741.3

p.G118*

c.352G>T

1 paper

NM_024741.3

p.W117*

c.351G>A

1 paper

NM_024741.3

p.W117*

c.350G>A

1 paper

NM_024741.3

p.S131Splc

c.393-9G>T

2 papers

NM_024741.3

p.R148Q

c.443G>A

1 paper

NM_001184751.2

p.L145F

c.433C>T