Varaico: Literature-Extracted Genetic Variants

ZNF408

129 papers

RefSeq Summary

The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein...

Pfam Domains

PRDM2_PRaa 61–179UCSCPR domain zinc finger protein 2, PR domain

zf-C2H2aa 381–403UCSCZinc finger, C2H2 type

zf-C2H2aa 409–431UCSCZinc finger, C2H2 type

zf-C2H2aa 437–459UCSCZinc finger, C2H2 type

zf-C2H2aa 468–490UCSCZinc finger, C2H2 type

zf-C2H2aa 496–518UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger protein 408

HGNC Alias Symbols

FLJ12827; PRDM17

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_024741.3

p.H455Y

c.1363C>T

Surrounding Variants

1 paper

NM_024741.3

p.R456C

c.1366C>T

2 papers

NM_024741.3

p.Q460*

c.1378C>T

4 papers

NM_024741.3

p.R448C

c.1342C>T

1 paper

NM_024741.3

p.K444R

c.1331A>G

2 papers

NM_024741.3

p.P436L

c.1307C>T

1 paper

NM_001184751.2

p.P428_F429delFs

c.1282_1285del4

1 paper

NM_024741.3

p.R435Q

c.1304G>A

1 paper

NM_024741.3

p.A478_N479insFs

c.1434_1435insC

1 paper

NM_001184751.2

p.V421M

c.1261G>A

1 paper

NM_024741.3

p.Q428*

c.1282C>T

1 paper

NM_024741.3

p.S482Y

c.1445C>A

5 papers

NM_024741.3

p.Q428_V429delFs

c.1282_1285del4