Varaico: Literature-Extracted Genetic Variants

ZNF408

129 papers

RefSeq Summary

The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein...

Pfam Domains

PRDM2_PRaa 61–179UCSCPR domain zinc finger protein 2, PR domain

zf-C2H2aa 381–403UCSCZinc finger, C2H2 type

zf-C2H2aa 409–431UCSCZinc finger, C2H2 type

zf-C2H2aa 437–459UCSCZinc finger, C2H2 type

zf-C2H2aa 468–490UCSCZinc finger, C2H2 type

zf-C2H2aa 496–518UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger protein 408

HGNC Alias Symbols

FLJ12827; PRDM17

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_024741.3

p.C581_T592del12

c.1741_1775del36

Surrounding Variants

1 paper

NM_024741.3

p.C581R

c.1741T>C

2 papers

NM_024741.3

p.P578S

c.1732C>T

NM_001184751.2

p.P570S

c.1708C>T

1 paper

NM_024741.3

p.Q583K

c.1747C>A

4 papers

NM_024741.3

p.E576_A587del12

c.1726_1760del36

1 paper

NM_024741.3

p.R586C

c.1756C>T

1 paper

NM_001184751.2

p.R578H

c.1733G>A

1 paper

NM_024741.3

p.A587_Y588ins6

c.1759_1763ins18

1 paper

NM_024741.3

p.R567*

c.1699C>T

1 paper

NM_024741.3

p.K593T

c.1778A>C

2 papers

NM_024741.3

p.L566H

c.1697T>A

1 paper

NM_024741.3

p.R596C

c.1786C>T

1 paper

NM_024741.3

p.P563_H564ins6

c.1687_1691ins18