Varaico: Literature-Extracted Genetic Variants

ZNF420

30 papers

RefSeq Summary

The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissocia...

Pfam Domains

KRABaa 5–46UCSCKRAB box

zf-C2H2aa 139–161UCSCZinc finger, C2H2 type

zf-C2H2aa 167–189UCSCZinc finger, C2H2 type

zf-C2H2aa 195–217UCSCZinc finger, C2H2 type

zf-C2H2aa 223–245UCSCZinc finger, C2H2 type

zf-C2H2aa 251–273UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger protein 420

HGNC Alias Symbol

FLJ32191

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_144689.5

p.L76P

c.227T>C

Surrounding Variants

1 paper

NM_144689.5

p.E77V

c.230A>T

1 paper

NM_144689.5

p.R75I

c.224G>T

1 paper

NM_144689.5

p.S73N

c.218G>A

2 papers

NM_144689.5

p.S68A

c.202T>G

1 paper

NM_144689.5

p.R150Q

c.449G>A

1 paper

NM_144689.5

p.C172R

c.514T>C

1 paper

NM_144689.5

p.G191A

c.572G>C

1 paper

NM_144689.5

p.A196E

c.587C>A

1 paper

NM_144689.5

p.A203T

c.607G>A

1 paper

NM_144689.5

p.K221N

c.663A>C

1 paper

NM_144689.5

p.K221N

c.663A>T

1 paper

NM_144689.5

p.N263H

c.787A>C