Varaico: Literature-Extracted Genetic Variants

ZNF420

30 papers

RefSeq Summary

The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissocia...

Pfam Domains

KRABaa 5–46UCSCKRAB box

zf-C2H2aa 139–161UCSCZinc finger, C2H2 type

zf-C2H2aa 167–189UCSCZinc finger, C2H2 type

zf-C2H2aa 195–217UCSCZinc finger, C2H2 type

zf-C2H2aa 223–245UCSCZinc finger, C2H2 type

zf-C2H2aa 251–273UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

zinc finger protein 420

HGNC Alias Symbol

FLJ32191

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_144689.5

p.M399K

c.1196T>A

Surrounding Variants

1 paper

NM_144689.5

p.P418T

c.1252C>A

1 paper

NM_144689.5

p.Q420E

c.1258C>G

1 paper

NM_144689.5

p.A427V

c.1280C>T

1 paper

NM_144689.5

p.N429S

c.1286A>G

1 paper

NM_144689.5

p.H297Y

c.889C>T

1 paper

NM_144689.5

p.Y279C

c.836A>G

1 paper

NM_144689.5

p.L268fs

c.802_803fs

1 paper

NM_144689.5

p.N263H

c.787A>C

1 paper

NM_144689.5

p.A541V

c.1622C>T

1 paper

NM_144689.5

p.I552N

c.1655T>A

1 paper

NM_144689.5

p.I552S

c.1655T>G

1 paper

NM_144689.5

p.Q573*

c.1717C>T