zinc and ring finger 1

nin283

FLJ14846

DKFZp434E229

zinc and ring finger 1, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase ZNRF1

Nerve injury-induced gene 283 protein

RING-type E3 ubiquitin transferase ZNRF1

Zinc/RING finger protein 1

This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. [provided by RefSeq, Feb 2012].

Varaico: Literature-Extracted Genetic Variants

ZNRF1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols