Varaico: Literature-Extracted Genetic Variants

ZP4

93 papers

RefSeq Summary

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimp...

Pfam Domains

ZP1_ZP4_Ig-likeaa 34–129UCSCZona pellucida sperm-binding proteins 1/4, Ig-like domain

Trefoilaa 143–182UCSCTrefoil (P-type) domain

ZP-Naa 189–288UCSCZP-N domain

Zona_pellucidaaa 311–456UCSCZP-C domain

Gene Aliases

HGNC Name

zona pellucida glycoprotein 4

HGNC Alias Symbols

ZPB; ZPB2; ZP1B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021186.5

p.S145A

c.433T>G

Surrounding Variants

1 paper

NM_021186.5

p.S145delFs

c.433_434delGA

1 paper

NM_021186.5

p.D144Y

c.430G>T

1 paper

NM_021186.5

p.P147L

c.440C>T

1 paper

NM_021186.5

p.T140A

c.418A>G

1 paper

NM_021186.5

p.A137V

c.410C>T

2 papers

NM_021186.5

p.R135*

c.403C>T

1 paper

NM_021186.5

p.A134T

c.400G>A

1 paper

NM_021186.5

p.I159_S160delFs

c.475_478del4

2 papers

NM_021186.5

p.S173C

c.518C>G

1 paper

NM_021186.5

p.V176M

c.526G>A

1 paper

NM_021186.5

p.T190I

c.569C>T

1 paper

NM_021186.5

p.C189_G193del0

c.565_579del15