Varaico: Literature-Extracted Genetic Variants

ZW10

56 papers

RefSeq Summary

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, w...

Pfam Domains

Zw10_Naa 27–119UCSCCentromere/kinetochore Zw10 N-terminal

Zw10_middleaa 177–415UCSCCentromere/kinetochore protein zw10, middle domain

ZW10_Caa 472–602UCSCCentromere/kinetochore protein zw10, C-terminal

ZW10_C2aa 624–778UCSCZW10 C-terminal helical domain

Gene Aliases

HGNC Name

zw10 kinetochore protein

HGNC Alias Symbol

KNTC1AP

Papers

RefSeq ID

Protein change

DNA change

1–12 of 56 variants

3 papers

NM_004724.4

p.R83W

c.247C>T

3 papers

NM_004724.4

p.A732P

c.2194G>C

2 papers

NM_004724.4

p.Q454*

c.1360C>T

2 papers

NM_004724.4

p.R562H

c.1685G>A

2 papers

NM_004724.4

p.S623G

c.1867A>G

1 paper

NM_004724.4

p.S12T

c.34T>A

1 paper

NM_004724.4

p.T22I

c.65C>T

1 paper

NM_004724.4

p.I34V

c.100A>G

1 paper

NM_004724.4

p.L59P

c.176T>C

1 paper

NM_004724.4

p.E80K

c.238G>A

1 paper

NM_004724.4

p.F115S

c.344T>C

1 paper

NM_004724.4

p.N123T

c.368A>C