Associated Papers
The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation.
Farnung J et al.
Biorxiv : the Preprint Server for Biology, 2026
The structural basis for RNA slicing by human Argonaute2.
Mohamed AA et al.
Cell Reports, 2025
Structural basis for gene silencing by siRNAs in humans.
Sarkar S et al.
Biorxiv : the Preprint Server for Biology, 2024
The structural basis for RNA slicing by human Argonaute2.
Mohamed AA et al.
Biorxiv : the Preprint Server for Biology, 2024
Dicer dependent tRNA derived small RNAs promote nascent RNA silencing.
Di Fazio A et al.
Nucleic Acids Research, 2022
Structural Basis for Target-Directed MicroRNA Degradation.
Sheu-Gruttadauria J et al.
Molecular Cell, 2019
Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology.
Zhang C et al.
Nature Communications, 2018
Small RNAs Recruit Chromatin-Modifying Enzymes MMSET and Tip60 to Reconfigure Damaged DNA upon Double-Strand Break and Facilitate Repair.
Wang Q et al.
Cancer Research, 2016
The roles of individual mammalian argonautes in RNA interference in vivo.
Ruda VM et al.
Plos One, 2014
Precursor microRNA-programmed silencing complex assembly pathways in mammals.
Liu X et al.
Molecular Cell, 2012
A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity.
Cifuentes D et al.
Science (new York, N.y.), 2010
A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.
O'Carroll D et al.
Genes & Development, 2007
Purified Argonaute2 and an siRNA form recombinant human RISC.
Rivas FV et al.
Nature Structural & Molecular Biology, 2005
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