Varaico: Literature-Extracted Genetic Variants

Gene:AKT1
Variant:p.G157S
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AKT1

NM_001382430.1:p.G157S

Associated Papers

Binimetinib and encorafenib for the treatment of advanced solid tumors with non-V600E BRAF mutations: results from the Phase II BEAVER trial.

Rose AAN et al.

Nature Communications, 2026

41484121 (PubMed )
Supplement: 41467_2025_68076_MOESM1_ESM.pdf

Real-World Evidence of the Prevalence of Driver Mutations in Anorectal Melanoma.

Jutten E et al.

Molecular Diagnosis & Therapy, 2025

Effects of chemotherapy combined with immunotherapy for non-small cell lung cancer with BRAF-mutations: a retrospective study.

Sun X et al.

American Journal of Cancer Research, 2025

Clinicopathological Features of Non-Small Cell Lung Carcinoma with BRAF Mutation.

Ambrosini-Spaltro A et al.

Current Oncology (toronto, Ont.), 2023

Co-mutations of epidermal growth factor receptor and BRAF in Chinese non-small cell lung cancer patients.

Peng P et al.

Annals of Translational Medicine, 2021

Clinicopathological and molecular characteristics of patients with hypermutant lung cancer: A retrospective cohort study.

Zhang H et al.

Oncology Letters, 2021

33692861 (PubMed )
Supplement: Supplementary_Data.pdf

Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Mack PC et al.

Cancer, 2020

Targeting oncogenic Raf protein-serine/threonine kinases in human cancers.

Roskoski R

Pharmacological Research, 2018

Detection of EGFR and BRAF mutations by competitive allele-specific TaqMan polymerase chain reaction in lung adenocarcinoma.

Yang Y et al.

Oncology Letters, 2018

Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Illei PB et al.

Oncotarget, 2017

29228562 (PubMed )
Supplement: oncotarget-08-96684-s001.pdf

Vulvar and vaginal melanoma: A unique subclass of mucosal melanoma based on a comprehensive molecular analysis of 51 cases compared with 2253 cases of nongynecologic melanoma.

Hou JY et al.

Cancer, 2017

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients.

Hsu HC et al.

Oncotarget, 2016

26989027 (PubMed )
Supplement: oncotarget-07-22257-s001.pdf

Genes involved in angiogenesis and mTOR pathways are frequently mutated in Asian patients with pancreatic neuroendocrine tumors.

Chou WC et al.

International Journal of Biological Sciences, 2016

27994516 (PubMed )
Supplement: ijbsv12p1523s1.xls › mutation_table

Molecular profiling of infiltrating urothelial carcinoma of bladder and nonbladder origin.

Millis SZ et al.

Clinical Genitourinary Cancer, 2015

Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma.

Guan J et al.

Scientific Reports, 2015

Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.

Griewank KG et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

BRAF mutation testing in clinical practice.

Ziai J et al.

Expert Review of Molecular Diagnostics, 2012

Molecular analysis of PIK3CA, BRAF, and RAS oncogenes in periampullary and ampullary adenomas and carcinomas.

Schönleben F et al.

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract, 2009

Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression.

Legrier ME et al.

Cancer Research, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."