Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

19 papers

NM_001382430.1

p.G157S

c.469G>A

Surrounding Variants

2 papers

NM_001382430.1

p.G157C

c.469G>T

3 papers

NM_001382430.1

p.G157R

c.469G>C

1 paper

NM_001382430.1

p.G157V

c.470G>T

1 paper

NM_001382430.1

p.L156R

c.467T>G

1 paper

NM_001382430.1

p.L156L

c.466C>T

1 paper

NM_001382430.1

p.L156M

c.466C>A

1 paper

NM_001382430.1

p.K158*

c.472A>T

1 paper

NM_001382430.1

p.K158R

c.473A>G

1 paper

NM_001382430.1

p.G159R

c.475G>C

1 paper

NM_001382430.1

p.G159S

c.475G>A

2 papers

NM_001382430.1

p.G159V

c.476G>T

1 paper

NM_001382430.1

p.G159D

c.476G>A