Varaico: Literature-Extracted Genetic Variants

Gene:AKT1
Variant:p.R76R
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AKT1

NM_001382430.1:p.R76R

Associated Papers

Disease-Specific and Histological Outcomes of Preoperative TERT Promoter Mutation Detected in Isolation or in Combination with Other Mutations in Thyroid Neoplasms.

Calcaterra M et al.

Thyroid : Official Journal of the American Thyroid Association, 2025

European Association of Neuro-Oncology guideline on molecular testing of meningiomas for targeted therapy selection.

Sahm F et al.

Neuro-oncology, 2025

39577862 (PubMed )
Supplement: noae253_suppl_supplementary_materials.docx

The Molecular Landscape of 227 Adult Granulosa Cell Tumors of the Ovary: Insights into the Progression from Primary to Recurrence.

Michálková R et al.

Laboratory Investigation; a Journal of Technical Methods and Pathology, 2025

Prognostic impact of genetic alterations and methylation classes in meningioma.

Berghoff AS et al.

Brain Pathology (zurich, Switzerland), 2022

35213082 (PubMed )
Supplement: BPA-32-e12970-s001.xlsx › Sheet1

AKT1E17K -mutated meningioma cell lines respond to treatment with the AKT inhibitor AZD5363.

John P et al.

Neuropathology and Applied Neurobiology, 2022

Molecular Pathology of Non-familial Follicular Epithelial-Derived Thyroid Cancer in Adults: From RAS/BRAF-like Tumor Designations to Molecular Risk Stratification.

Soares P et al.

Endocrine Pathology, 2021

Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ?

Gomes-Lima CJ et al.

Frontiers in Endocrinology, 2021

Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas.

González-Tablas M et al.

Frontiers in Oncology, 2021

34868937 (PubMed )
Supplement: DataSheet_1.docx

Metastatic Anaplastic Thyroid Carcinoma in Complete Remission: Morphological, Molecular, and Clinical Work-Up of a Rare Case.

Stenman A et al.

Endocrine Pathology, 2020

Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers.

Pozdeyev N et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018

Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas.

Juratli TA et al.

Oncotarget, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."