Varaico: Literature-Extracted Genetic Variants

AKT1

3,188 papers

RefSeq Summary

This gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT prot...

Pfam Domains

PHaa 6–108UCSCPH domain

Pkinaseaa 150–408UCSCProtein kinase domain

Pkinase_Caa 429–474UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 1

HGNC Alias Symbols

PKB; PRKBA; RAC-alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_001382430.1

p.R76R

c.228C>T

Surrounding Variants

1 paper

NM_001382430.1

p.R76R

c.228C>A

2 papers

NM_001382430.1

p.Q61_R76ins5

c.181_228dup48

1 paper

NM_001382430.1

p.R76ins14

c.227_228ins42

5 papers

NM_001382430.1

p.R76H

c.227G>A

9 papers

NM_001382430.1

p.C77F

c.230G>T

5 papers

NM_001382430.1

p.R76C

c.226C>T

1 paper

NM_001382430.1

p.R76ins12

c.226_227ins36

1 paper

NM_001382430.1

p.R76_C77ins13

c.226_230ins39

4 papers

NM_001382430.1

p.I75M

c.225C>G

1 paper

NM_001382430.1

p.M63_I75ins4

c.189_224dup36

2 papers

NM_001382430.1

p.R69_C77ins3

c.207_230dup24

1 paper

NM_001382430.1

p.R67_C77ins3

c.201_230dup30