Associated Papers
Is Predisposition to T2D Impacted by Polymorphisms in Genes Involved in Insulin Signaling and Cellular Bioenergetics?
Pati B et al.
Acta Physiologica (oxford, England), 2025
Discriminating activating, deactivating and resistance variants in protein kinases.
Singh G et al.
Genome Medicine, 2025
41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S6
Genetics of metabolic traits in Greenlanders.
Thuesen ACB et al.
Danish Medical Journal, 2023
In Silico Investigation of AKT2 Gene and Protein Abnormalities Reveals Potential Association with Insulin Resistance and Type 2 Diabetes.
Elangeeb ME et al.
Current Issues in Molecular Biology, 2023
Prioritization of genes associated with type 2 diabetes mellitus for functional studies.
Tan WX et al.
Nature Reviews. Endocrinology, 2023
Finnish-specific AKT2 gene variant leads to impaired insulin signalling in myotubes.
Mäkinen S et al.
Journal of Molecular Endocrinology, 2023
FinnGen provides genetic insights from a well-phenotyped isolated population.
Kurki MI et al.
Nature, 2023
36653562 (PubMed )
Supplement: 41586_2022_5473_MOESM4_ESM.xlsx › Supplementary_Table_11
Insulin resistance and exaggerated insulin sensitivity triggered by single-gene mutations in the insulin signaling pathway.
Kushi R et al.
Diabetology International, 2021
The molecular landscape of ETMR at diagnosis and relapse.
Lambo S et al.
Nature, 2019
31802000 (PubMed )
Supplement: NIHMS1541318-supplement-Supplementary_Table_6.xlsx › SNVs_Targeted_Sequencing
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Flannick J et al.
Nature, 2019
31118516 (PubMed )
Supplement: 41586_2019_1231_MOESM1_ESM.pdf
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.
Gabbouj S et al.
Neurobiology of Aging, 2019
Genetics of metabolic traits in Greenlanders: lessons from an isolated population.
Andersen MK et al.
Journal of Internal Medicine, 2018
Genomic insights into the causes of type 2 diabetes.
Langenberg C et al.
Lancet (london, England), 2018
A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study.
Latva-Rasku A et al.
Diabetes, 2018
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Manning A et al.
Diabetes, 2017
Whole-exome sequencing of Finnish hereditary breast cancer families.
Määttä K et al.
European Journal of Human Genetics : Ejhg, 2016
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