Varaico: Literature-Extracted Genetic Variants

Gene:AKT2
Variant:p.P50T

AKT2

617 papers

RefSeq Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The...

Pfam Domains

PHaa 6–108UCSCPH domain
Pkinaseaa 152–409UCSCProtein kinase domain
Pkinase_Caa 430–475UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

AKT serine/threonine kinase 2

HGNC Alias Symbol

PKBβ

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
16 papers
NM_001626.6
p.P50T
c.148C>A
Surrounding Variants
1 paper
NM_001626.6
p.P50A
c.148C>G
1 paper
NM_001626.6
p.P50P
c.150C>T
1 paper
NM_001626.6
p.P51A
c.151C>G
1 paper
NM_001626.6
p.L49I
c.145C>A
1 paper
NM_001626.6
p.P51R
c.152C>G
1 paper
NM_001626.6
p.L52*
c.155T>G
1 paper
NM_001626.6
p.L52*
c.155T>A
1 paper
NM_001626.6
p.Q47H
c.141G>T
1 paper
NM_001626.6
p.Q47H
c.141G>C
1 paper
NM_001626.6
p.Q47*
c.139C>T
1 paper
NM_001626.6
p.N53Y
c.157A>T
1 paper
NM_001626.6
p.N53H
c.157A>C
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