Associated Papers
Zinc-mediated allosteric inhibition of caspase-6.
Velázquez-Delgado EM et al.
The Journal of Biological Chemistry, 2012
Molecular insight into the role of the leucine residue on the L2 loop in the catalytic activity of caspases 3 and 7.
Kang HJ et al.
Bioscience Reports, 2012
Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.
Walters J et al.
Archives of Biochemistry and Biophysics, 2011
Melody, an ENU mutation in Caspase 3, alters the catalytic cysteine residue and causes sensorineural hearing loss in mice.
Parker A et al.
Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2010
A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis.
Walters J et al.
The Biochemical Journal, 2009
Mutations in the procaspase-3 dimer interface affect the activity of the zymogen.
Pop C et al.
Biochemistry, 2003
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