Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.C163S

CASP3

926 papers

RefSeq Summary

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) p...

Pfam Domains

Peptidase_C14aa 44–274UCSCCaspase domain

Gene Aliases

HGNC Name

caspase 3

HGNC Alias Symbols

CPP32; CPP32B; Yama; apopain

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_004346.4
p.C163S
c.487T>A
Surrounding Variants
6 papers
NM_004346.4
p.C163S
c.488G>C
1 paper
NM_004346.4
p.C163W
c.489C>G
1 paper
NM_004346.4
p.E167A
c.500A>C
1 paper
NM_004346.4
p.L168V
c.502C>G
3 papers
NM_004346.4
p.D169G
c.506A>G
1 paper
NM_004346.4
p.D169A
c.506A>C
1 paper
NM_004346.4
p.C170R
c.508T>C
1 paper
NM_004346.4
p.C170S
c.508T>A
1 paper
NM_004346.4
p.C170F
c.509G>T
1 paper
NM_004346.4
p.C170S
c.509G>C
1 paper
NM_004346.4
p.G171R
c.511G>C
2 papers
NM_004346.4
p.E173A
c.518A>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."