Varaico: Literature-Extracted Genetic Variants

Gene:CRBN
Variant:p.E377V
Back to variants list

CRBN

NM_016302.4:p.E377V

Associated Papers

A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation.

Langousis G et al.

Nature Communications, 2025

Thalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4.

Belair DG et al.

Scientific Reports, 2020

Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon.

Akuffo AA et al.

The Journal of Biological Chemistry, 2018

A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.

Matyskiela ME et al.

Nature, 2016

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."