Varaico: Literature-Extracted Genetic Variants

CRBN

173 papers

RefSeq Summary

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and ...

Pfam Domains

LON_substr_bdgaa 80–317UCSCATP-dependent protease La (LON) substrate-binding domain

Yippee-Mis18aa 319–437UCSCYippee zinc-binding/DNA-binding /Mis18, centromere assembly

Gene Aliases

HGNC Name

cereblon

HGNC Previous Symbol

MRT2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_016302.4

p.E377V

c.1130A>T

Surrounding Variants

1 paper

NM_016302.4

p.E377A

c.1130A>C

3 papers

NM_016302.4

p.E377K

c.1129G>A

1 paper

NM_016302.4

p.H378N

c.1132C>A

1 paper

NM_016302.4

p.T376A

c.1126A>G

1 paper

NM_016302.4

p.S379R

c.1135A>C

1 paper

NM_016302.4

p.S379N

c.1136G>A

1 paper

NM_016302.4

p.S379R

c.1137C>G

1 paper

NM_016302.4

p.S379R

c.1137C>A

1 paper

NM_016302.4

p.P374fs

c.1120_1121fs

1 paper

NM_016302.4

p.R373_P374delFs

c.1119_1120delGC

1 paper

NM_016302.4

p.F381C

c.1142T>G

3 papers

NM_016302.4

p.F381S

c.1142T>C