Varaico: Literature-Extracted Genetic Variants

Gene:GRIK3
Variant:p.S310A
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GRIK3

NM_000831.4:p.S310A

Associated Papers

Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis.

Rajeh A et al.

Medrxiv : the Preprint Server for Health Sciences, 2023

37808834 (PubMed )
Supplement: media-2.xlsx › pnSomatic_supplement_tableS2

Ultrarare Loss-of-Function Mutations in the Genes Encoding the Ionotropic Glutamate Receptors of Kainate Subtypes Associated with Schizophrenia Disrupt the Interaction with PSD95.

Hu TM et al.

Journal of Personalized Medicine, 2022

35629206 (PubMed )
Supplement: jpm-12-00783-s001.zip › Supplementary_Figures_1.pdf

Whole genome mapping and identification of single nucleotide polymorphisms of four Bangladeshi individuals and their functional significance.

Khan S et al.

Bmc Research Notes, 2021

33743798 (PubMed )
Supplement: 13104_2021_5514_MOESM4_ESM.zip › Supplementary_File_1A-1.xlsx › Supplementary_File_1A-1.exonic_

Pharmacogenetics of drug dependence: Polymorphisms of genes involved in glutamate neurotransmission.

Nudmamud-Thanoi S et al.

Neuroscience Letters, 2020

Damaging coding variants within kainate receptor channel genes are enriched in individuals with schizophrenia, autism and intellectual disabilities.

Koromina M et al.

Scientific Reports, 2019

CALCA and TRPV1 genes polymorphisms are related to a good outcome in female chronic migraine patients treated with OnabotulinumtoxinA.

Moreno-Mayordomo R et al.

The Journal of Headache and Pain, 2019

Identification of pathways and genes associated with cerebral palsy.

Zhu Q et al.

Genes & Genomics, 2018

Association between N-methyl-D-aspartate Receptor Subunit 2B Gene Polymorphisms and Personality Traits in a Young Japanese Population.

Narita S et al.

East Asian Archives of Psychiatry : Official Journal of the Hong Kong College of Psychiatrists = Dong Ya Jing Shen Ke Xue Zhi : Xianggang Jing Shen Ke Yi Xue Yuan Qi Kan, 2018

Genetic susceptibility to postherniotomy pain. The influence of polymorphisms in the Mu opioid receptor, TNF-α, GRIK3, GCH1, BDNF and CACNA2D2 genes.

Kalliomäki ML et al.

Scandinavian Journal of Pain, 2016

Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases.

Yuan H et al.

Molecular Pharmacology, 2015

Genetics of alcohol dependence: a review of clinical studies.

Samochowiec J et al.

Neuropsychobiology, 2014

Family-based and case-control study of glutamate receptor GRIK3 Ser310Ala polymorphism in alcohol dependence.

Grzywacz A et al.

European Addiction Research, 2013

Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Gnad F et al.

Bmc Genomics, 2013

23819521 (PubMed )
Supplement: 1471-2164-14-S3-S7-S1.xlsx › dbSNP

Genetics of schizophrenia from a clinicial perspective.

Kukshal P et al.

International Review of Psychiatry (abingdon, England), 2012

Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures.

Kim JH et al.

Plos One, 2011

21283641 (PubMed )
Supplement: pone.0016331.s001.doc

Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: a decade of advance.

Cherlyn SY et al.

Neuroscience and Biobehavioral Reviews, 2010

Are GRIK3 (T928G) gene variants in schizophrenia patients different from those in their first-degree relatives?

Kilic G et al.

Psychiatry Research, 2010

Pharmacogenetics of alcohol and alcohol dependence treatment.

Kranzler HR et al.

Current Pharmaceutical Design, 2010

The identification and functional implications of human-specific "fixed" amino acid substitutions in the glutamate receptor family.

Goto H et al.

Bmc Evolutionary Biology, 2009

A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE).

Djurovic S et al.

Schizophrenia Research, 2009

An association of GRIK3 Ser310Ala functional polymorphism with personality traits.

Minelli A et al.

Neuropsychobiology, 2009

Association between the ionotropic glutamate receptor kainate3 (GRIK3) Ser310Ala polymorphism and schizophrenia in the Indian population.

Ahmad Y et al.

The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry, 2009

Association of the human kainate receptor GluR7 gene (GRIK3) with recurrent major depressive disorder.

Schiffer HH et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2007

Family-based and case-control association studies of glutamate receptor GRIK3 Ser310Ala polymorphism in Polish patients and families with alcohol dependence.

Samochowiec J et al.

Neuroscience Letters, 2006

The relationship between the pharmacology of antiepileptic drugs and human gene variation: an overview.

Ferraro TN et al.

Epilepsy & Behavior : E&b, 2005

No association between the ionotropic glutamate receptor kainate 3 gene ser310ala polymorphism and schizophrenia.

Lai IC et al.

Neuropsychobiology, 2005

Candidate gene studies of human pain mechanisms: methods for optimizing choice of polymorphisms and sample size.

Belfer I et al.

Anesthesiology, 2004

Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder.

Delorme R et al.

Neuroreport, 2004

Association between the ionotropic glutamate receptor kainate 3 (GRIK3) ser310ala polymorphism and schizophrenia.

Begni S et al.

Molecular Psychiatry, 2002

Ionotropic glutamate receptor gene GRIK3 SER310ALA functional polymorphism is related to delirium tremens in alcoholics.

Preuss UW et al.

The Pharmacogenomics Journal, 0

[Association studies of dopamine D4 receptor gene exon 3 in patients with alcohol dependence].

Grzywacz A et al.

Psychiatria Polska, 0

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