Varaico: Literature-Extracted Genetic Variants

GRIK3

180 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 55–400UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 434–548UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 562–832UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 3

HGNC Alias Symbols

GluK3; GLUR7

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

31 papers

NM_000831.4

p.S310A

c.928T>G

Surrounding Variants

2 papers

NM_000831.4

p.S310P

c.928T>C

1 paper

NM_000831.4

p.R309_S310insFs

c.927_928insT

1 paper

NM_000831.4

p.R309W

c.925C>T

1 paper

NM_000831.4

p.A307A

c.921T>A

1 paper

NM_000831.4

p.Q305R

c.914A>G

1 paper

NM_000831.4

p.R303W

c.907C>T

1 paper

NM_000831.4

p.V287V

c.861G>C

1 paper

NM_000831.4

p.R273H

c.818G>A

1 paper

NM_000831.4

p.L267S

c.800T>C

1 paper

NM_000831.4

p.D328N

c.982G>A

2 papers

NM_000831.4

p.V330I

c.988G>A

1 paper

NM_000831.4

p.V335L

c.1003G>T