Varaico: Literature-Extracted Genetic Variants

Gene:GRK2
Variant:p.D527A
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GRK2

NM_001619.5:p.D527A

Associated Papers

Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation.

Baameur F et al.

Molecular Pharmacology, 2010

GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail.

Sterne-Marr R et al.

Biochemistry, 2009

Phosphorylation-independent regulation of metabotropic glutamate receptor 1 signaling requires g protein-coupled receptor kinase 2 binding to the second intracellular loop.

Dhami GK et al.

The Journal of Biological Chemistry, 2005

Involvement of the C-terminal proline-rich motif of G protein-coupled receptor kinases in recognition of activated rhodopsin.

Gan X et al.

The Journal of Biological Chemistry, 2004

G Protein-coupled receptor kinase 2 regulator of G protein signaling homology domain binds to both metabotropic glutamate receptor 1a and Galphaq to attenuate signaling.

Dhami GK et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."