Varaico: Literature-Extracted Genetic Variants

Gene:GRM2
Variant:p.G689V
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GRM2

NM_000839.5:p.G689V

Associated Papers

Structural determinants of allosteric antagonism at metabotropic glutamate receptor 2: mechanistic studies with new potent negative allosteric modulators.

Lundström L et al.

British Journal of Pharmacology, 2011

Transposition of three amino acids transforms the human metabotropic glutamate receptor (mGluR)-3-positive allosteric modulation site to mGluR2, and additional characterization of the mGluR2-positive allosteric modulation site.

Rowe BA et al.

The Journal of Pharmacology and Experimental Therapeutics, 2008

Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2.

Schaffhauser H et al.

Molecular Pharmacology, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."