Associated Papers
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide.
Guerra G et al.
Neuro-oncology, 2025
Identifying active and inhibitor-resistant MGMT variants for gene therapy.
Cheong A et al.
American Journal of Human Genetics, 2025
Evaluation of mutations on O6-methylguanine methyl transferase structure and its interactions: molecular dynamics simulation study.
Gharouni M et al.
Journal of Biomolecular Structure & Dynamics, 2025
Integrative Computational Analysis of Common EXO5 Haplotypes: Impact on Protein Dynamics, Genome Stability, and Cancer Progression.
Mazza F et al.
Journal of Chemical Information and Modeling, 2025
Genetic polymorphisms, methylation, and expression levels in the GSTP1 and MGMT genes in urothelial bladder tumors.
Serpeloni JM et al.
Gene, 2025
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide.
Guerra G et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Mutation analysis of the TERT gene in ovarian cancer patients of the Turkish population by next generation sequencing method.
Capar Gorali B et al.
Cellular and Molecular Biology (noisy-le-grand, France), 2023
Genetic and epigenetic alterations in MGMT gene and correlation with concomitant chemoradiotherapy (CRT) in cervical cancer.
Gupta MK et al.
Journal of Cancer Research and Clinical Oncology, 2023
Brain radiotoxicity-related 15CAcBRT gene expression signature predicts survival prognosis of glioblastoma patients.
Reyes-González J et al.
Neuro-oncology, 2023
Temozolomide-induced myelotoxicity and single nucleotide polymorphisms in the MGMT gene in patients with adult diffuse glioma: a single-institutional pharmacogenetic study.
Moitra P et al.
Journal of Neuro-oncology, 2022
Gene polymorphisms and risk of head and neck squamous cell carcinoma: a systematic review.
Rajabi-Moghaddam M et al.
Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2022
The Role of O6-methylguanine-DNA Methyltransferase Polymorphisms in Prostate Cancer Susceptibility: a Meta-Analysis.
Zhang W et al.
Pathology Oncology Research : Por, 2020
Impact of rs12917 MGMT Polymorphism on [18F]FDG-PET Response in Pediatric Hodgkin Lymphoma (PHL).
Kewitz-Hempel S et al.
Molecular Imaging and Biology, 2019
The potential role of MGMT rs12917 polymorphism in cancer risk: an updated pooling analysis with 21010 cases and 34018 controls.
Sheng Z et al.
Bioscience Reports, 2018
Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases.
FitzGerald LM et al.
Prostate Cancer and Prostatic Diseases, 2018
Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.
Wang J et al.
Scientific Reports, 2017
MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case.
Altinoz MA et al.
Journal of Chemotherapy (florence, Italy), 2017
The Association of Low-Penetrance Variants in DNA Repair Genes with Colorectal Cancer: A Systematic Review and Meta-Analysis.
Aggarwal N et al.
Clinical and Translational Gastroenterology, 2017
The intricate interplay between MSI and polymorphisms of DNA repair enzymes in gastric cancer H.pylori associated.
Silva-Fernandes IJL et al.
Mutagenesis, 2017
Genetic profiling of a rare condition: co-occurrence of albinism and multiple primary melanoma in a Caucasian family.
De Summa S et al.
Oncotarget, 2017
The MGMT promoter single-nucleotide polymorphism rs1625649 had prognostic impact on patients with MGMT methylated glioblastoma.
Hsu CY et al.
Plos One, 2017
Clinical and Genetic Factors Associated With Severe Hematological Toxicity in Glioblastoma Patients During Radiation Plus Temozolomide Treatment: A Prospective Study.
Lombardi G et al.
American Journal of Clinical Oncology, 2015
Genetic Association Between Angiotensinogen Polymorphisms and Lung Cancer Risk.
Wang H et al.
Medicine, 2015
The role of O(6)-methylguanine-DNA methyltransferase polymorphisms in colorectal cancer susceptibility: a meta analysis.
Lu Y et al.
International Journal of Clinical and Experimental Medicine, 2015
A steroid metabolizing gene variant in a polyfactorial model improves risk prediction in a high incidence breast cancer population.
Jupe ER et al.
Bba Clinical, 2014
Human papillomavirus and host genetic polymorphisms in carcinogenesis: a systematic review and meta-analysis.
Habbous S et al.
Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology, 2014
Deletion of the MGMT gene in familial melanoma.
Appelqvist F et al.
Genes, Chromosomes & Cancer, 2014
MGMT gene silencing by promoter hypermethylation in gastric cancer in a high incidence area.
Yousuf A et al.
Cellular Oncology (dordrecht, Netherlands), 2014
Tumor-associated mutations in O⁶ -methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality.
Lamb KL et al.
Molecular Carcinogenesis, 2014
Association between six genetic polymorphisms and colorectal cancer: a meta-analysis.
Chen C et al.
Genetic Testing and Molecular Biomarkers, 2014
Identification of methylguanine methyltransferase polymorphisms as genetic markers of individual susceptibility to therapy-related myeloid neoplasms.
Dubois J et al.
European Journal of Cancer (oxford, England : 1990), 2014
Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.
Wang J et al.
Plos One, 2014
Splice site and Germline variations of the MGMT gene in Esophageal cancer from Kashmir Valley: India.
Shah MA et al.
International Journal of Health Sciences, 2013
The polymorphisms in the MGMT gene and the risk of cancer: a meta-analysis.
Du L et al.
Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013
DNA repair gene variants in relation to overall cancer risk: a population-based study.
Alberg AJ et al.
Carcinogenesis, 2013
MGMT Leu84Phe polymorphism contributes to cancer susceptibility: evidence from 44 case-control studies.
Liu J et al.
Plos One, 2013
DNA mismatch repair network gene polymorphism as a susceptibility factor for pancreatic cancer.
Dong X et al.
Molecular Carcinogenesis, 2012
SNP-SNP interactions between DNA repair genes were associated with breast cancer risk in a Korean population.
Han W et al.
Cancer, 2012
Lack of influence of MGMT codon Leu84Phe and codon Ileu143Val polymorphisms on esophageal cancer risk in the Kashmir Valley.
Shah MA et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2012
Polymorphisms associated with the risk of lung cancer in a healthy Mexican Mestizo population: Application of the additive model for cancer.
Pérez-Morales R et al.
Genetics and Molecular Biology, 2011
Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia.
Shi JY et al.
International Journal of Cancer, 2011
Temozolomide-induced severe myelosuppression: analysis of clinically associated polymorphisms in two patients.
Sylvester RK et al.
Anti-cancer Drugs, 2011
Sequence Variants and the Risk of Head and Neck Cancer: Pooled Analysis in the INHANCE Consortium.
Chuang SC et al.
Frontiers in Oncology, 2011
Genotoxic thresholds, DNA repair, and susceptibility in human populations.
Jenkins GJ et al.
Toxicology, 2010
O6-methylguanine-DNA methyltransferase gene coding region polymorphisms and oral cancer risk.
Huang SH et al.
Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2010
MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.
Loh YH et al.
Dna Repair, 2010
Effects of O6-methylguanine-DNA methyltransferase (MGMT) polymorphisms on cancer: a meta-analysis.
Zhong Y et al.
Mutagenesis, 2010
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.
Rajaraman P et al.
Neuro-oncology, 2010