Varaico: Literature-Extracted Genetic Variants

Gene:MYC
Variant:p.P57S
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MYC

NM_002467.6:p.P57S

Associated Papers

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations.

Kliche J et al.

Molecular Systems Biology, 2024

39009827 (PubMed )
Supplement: 44320_2024_55_MOESM5_ESM.xlsx › A-binding_peptides

Plasmablastic lymphoma: from genetics to treatment.

Frontzek F et al.

Leukemia & Lymphoma, 2023

Bioinformatic prediction of putative conveyers of O-GlcNAc transferase intellectual disability.

Mitchell CW et al.

The Journal of Biological Chemistry, 2022

35863433 (PubMed )
Supplement: mmc4.xlsx › -1_position

Characterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing.

Lang GT et al.

Nature Communications, 2020

33173047 (PubMed )
Supplement: 41467_2020_19342_MOESM7_ESM.xlsx › PGI_fudan_NC_clnical.oc

Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit.

Cucco F et al.

Leukemia, 2020

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma.

López C et al.

Nature Communications, 2019

Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma.

Xu-Monette ZY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

A common functional consequence of tumor-derived mutations within c-MYC.

Chakraborty AA et al.

Oncogene, 2015

24998853 (PubMed )
Supplement: NIHMS593237-supplement-7.pdf

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Witkiewicz AK et al.

Nature Communications, 2015

25855536 (PubMed )
Supplement: ncomms7744-s2.xlsx › MUTATIONS_ALL_CASES

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Holehouse AS et al.

Plos One, 2015

26659599 (PubMed )
Supplement: pone.0144692.s002.xlsx › suppTable_2.txt

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

MacConaill LE et al.

The Journal of Molecular Diagnostics : Jmd, 2014

Burkitt's lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis.

Cowling VH et al.

Oncogene, 2014

Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.

Gysin S et al.

Molecular Cancer Research : Mcr, 2012

Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma.

Deshpande V et al.

Bmc Cancer, 2011

21303542 (PubMed )
Supplement: 1471-2407-11-60-S1.XLS › Table_1_OM3_core_sites

Profiling critical cancer gene mutations in clinical tumor samples.

MacConaill LE et al.

Plos One, 2009

19924296 (PubMed )
Supplement: pone.0007887.s002.xls › Table_S1_

Quantifying the role of aberrant somatic hypermutation in transformation of follicular lymphoma.

Halldórsdóttir AM et al.

Leukemia Research, 2008

Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells.

Cheung RS et al.

Carcinogenesis, 2007

Mutational analysis of MYC in common epithelial cancers and acute leukemias.

Lee JW et al.

Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2006

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.

Hemann MT et al.

Nature, 2005

c-myc box II mutations in Burkitt's lymphoma-derived alleles reduce cell-transformation activity and lower response to broad apoptotic stimuli.

Kuttler F et al.

Oncogene, 2001

The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals.

Chang DW et al.

Molecular and Cellular Biology, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."