Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

21 papers

NM_002467.6

p.P57S

c.169C>T

Surrounding Variants

2 papers

NM_002467.6

p.P57T

c.169C>A

2 papers

NM_002467.6

p.P57A

c.169C>G

3 papers

NM_002467.6

p.P57L

c.170C>T

1 paper

NM_002467.6

p.Q56H

c.168G>C

2 papers

NM_002467.6

p.P57delFs

c.169delC

2 papers

NM_002467.6

p.Q56_P57delins

c.168_170delinsTAA

1 paper

NM_002467.6

p.Q56P

c.167A>C

1 paper

NM_002467.6

p.P57P

c.171C>A

1 paper

NM_002467.6

p.P57P

c.171C>G

1 paper

NM_002467.6

p.P58T

c.172C>A

1 paper

NM_002467.6

p.P58fs

c.172_173fs

1 paper

NM_002467.6

p.P58L

c.173C>T