Associated Papers
The multimerization pathway of the glucocorticoid receptor.
Alegre-Martí A et al.
Nucleic Acids Research, 2025
Quaternary glucocorticoid receptor structure highlights allosteric interdomain communication.
Postel S et al.
Nature Structural & Molecular Biology, 2023
Zebrafish Mutant Lines Reveal the Interplay between nr3c1 and nr3c2 in the GC-Dependent Regulation of Gene Transcription.
Dinarello A et al.
International Journal of Molecular Sciences, 2022
The glucocorticoid receptor DNA-binding domain recognizes RNA hairpin structures with high affinity.
Parsonnet NV et al.
Nucleic Acids Research, 2019
Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization.
Van Looveren K et al.
Plos One, 2019
Relationship Between Homodimeric Glucocorticoid Receptor and Transcriptional Regulation Assessed via an In Vitro Fluorescence Correlation Spectroscopy-Microwell System.
Oasa S et al.
Scientific Reports, 2018
DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin.
Coons LA et al.
Endocrinology, 2017
Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor.
Presman DM et al.
Plos Biology, 2014
Complex human glucocorticoid receptor dim mutations define glucocorticoid induced apoptotic resistance in bone cells.
Jewell CM et al.
Molecular Endocrinology (baltimore, Md.), 2012
DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Krüppel-like factor 15 gene expression.
Asada M et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 2011
Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.
Frijters R et al.
Bmc Genomics, 2010
Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription in GR-deficient BE(2)C and T84 cells in vitro.
Tsugita M et al.
Molecular and Cellular Endocrinology, 2009
The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene.
Waddell DS et al.
American Journal of Physiology. Endocrinology and Metabolism, 2008
Genetic dissection of glucocorticoid receptor function in the mouse brain.
Erdmann G et al.
Journal of Neuroendocrinology, 2008
Glucocorticoid receptor is required for skin barrier competence.
Bayo P et al.
Endocrinology, 2008
Glucocorticoid receptor physiology.
Heitzer MD et al.
Reviews in Endocrine & Metabolic Disorders, 2007
The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction.
Liberman AC et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2007
Arsenic disruption of steroid receptor gene activation: Complex dose-response effects are shared by several steroid receptors.
Bodwell JE et al.
Chemical Research in Toxicology, 2006
Functional characterization of the natural human glucocorticoid receptor (hGR) mutants hGRalphaR477H and hGRalphaG679S associated with generalized glucocorticoid resistance.
Charmandari E et al.
The Journal of Clinical Endocrinology and Metabolism, 2006
Evaluation of steroid receptor function by gene targeting in mice.
Wintermantel TM et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2005
The human glucocorticoid receptor (hGR) beta isoform suppresses the transcriptional activity of hGRalpha by interfering with formation of active coactivator complexes.
Charmandari E et al.
Molecular Endocrinology (baltimore, Md.), 2005
Interaction of the glucocorticoid receptor and the chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII): implications for the actions of glucocorticoids on glucose, lipoprotein, and xenobiotic metabolism.
De Martino MU et al.
Annals of the New York Academy of Sciences, 2004
The glucocorticoid receptor and the orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II interact with and mutually affect each other's transcriptional activities: implications for intermediary metabolism.
De Martino MU et al.
Molecular Endocrinology (baltimore, Md.), 2004
Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta action.
Li G et al.
The Journal of Biological Chemistry, 2003
Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms.
Bray PJ et al.
Human Mutation, 2003
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition.
Bledsoe RK et al.
Cell, 2002
Corticosteroid receptors in the brain: gene targeting studies.
Kellendonk C et al.
Brain Research Bulletin, 2002
Mapping of glucocorticoid receptor DNA binding domain surfaces contributing to transrepression of NF-kappa B and induction of apoptosis.
Tao Y et al.
The Journal of Biological Chemistry, 2001
Cooperation among Stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes.
Aittomäki S et al.
Journal of Immunology (baltimore, Md. : 1950), 2000
Molecular genetic dissection of glucocorticoid receptor function in vivo.
Reichardt HM et al.
Zeitschrift Fur Rheumatologie, 2000
Glucocorticoid-stimulated gene expression knocked out by knock-in mutation.
Berg JP
European Journal of Endocrinology, 1998
Genetic dissection of glucocorticoid receptor function in mice.
Tronche F et al.
Current Opinion in Genetics & Development, 1998
DNA binding of the glucocorticoid receptor is not essential for survival.
Reichardt HM et al.
Cell, 1998
Analysis of glucocorticoid signalling by gene targeting.
Reichardt HM et al.
The Journal of Steroid Biochemistry and Molecular Biology, 1998
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.
Heck S et al.
The Embo Journal, 1994
Mutagenesis of the glucocorticoid receptor in mice.
Kellendonk C et al.
The Journal of Steroid Biochemistry and Molecular Biology, 0