Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

36 papers

NM_000176.3

p.E153V

c.458A>T

Surrounding Variants

1 paper

NM_000176.3

p.K154Q

c.460A>C

1 paper

NM_000176.3

p.K154R

c.461A>G

1 paper

NM_000176.3

p.P151T

c.451C>A

1 paper

NM_000176.3

p.A150A

c.450C>T

1 paper

NM_000176.3

p.A150T

c.448G>A

1 paper

NM_000176.3

p.A149V

c.446C>T

1 paper

NM_000176.3

p.A146G

c.437C>G

1 paper

NM_000176.3

p.S164F

c.491C>T

1 paper

NM_000176.3

p.S164delFs

c.491delG

1 paper

NM_000176.3

p.S165A

c.493T>G

1 paper

NM_000176.3

p.K140N

c.420G>T

1 paper

NM_000176.3

p.K140N

c.420G>C