Associated Papers
The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis.
Durumutla HB et al.
The Journal of Clinical Investigation, 2025
The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel prometabolic targets of the glucocorticoid receptor in muscle.
Prabakaran AD et al.
Science Advances, 2025
The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis.
Durumutla HB et al.
Biorxiv : the Preprint Server for Biology, 2025
The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle.
Prabakaran AD et al.
Biorxiv : the Preprint Server for Biology, 2025
Genetic variants in patients with multiple arterial aneurysms.
Körfer D et al.
Langenbeck's Archives of Surgery, 2024
Glucocorticoid Receptor Gene (NR3C1) Polymorphisms and Metabolic Syndrome: Insights from the Mennonite Population.
Kolb KL et al.
Genes, 2023
NGS study of glucocorticoid response genes in inflammatory bowel disease patients.
Skrzypczak-Zielinska M et al.
Archives of Medical Science : Ams, 2021
Uncovering a multitude of human glucocorticoid receptor variants: an expansive survey of a single gene.
Leventhal SM et al.
Bmc Genetics, 2019
The Associations of PMF1, ICAM1, AGT, TRIM65, FBF1, and ACOX1 Variants With Leukoaraiosis in Chinese Population.
Huang WQ et al.
Frontiers in Genetics, 2019
Glucocorticoid Receptor Mutations and Hypersensitivity to Endogenous and Exogenous Glucocorticoids.
Santen RJ et al.
The Journal of Clinical Endocrinology and Metabolism, 2018
A polymorphism in the glucocorticoid receptor gene is associated with refractory hypotension in premature infants.
Ogasawara K et al.
Pediatrics and Neonatology, 2018
Significant prevalence of NR3C1 mutations in incidentally discovered bilateral adrenal hyperplasia: results of the French MUTA-GR Study.
Vitellius G et al.
European Journal of Endocrinology, 2018
Correlation between polymorphisms of the NR3C1 gene and glucocorticoid effectiveness in patients with pemphigus vulgaris.
Fang SY et al.
Scientific Reports, 2017
Donor Genotype and Intragraft Expression of CYP3A5 Reflect the Response to Steroid Treatment During Acute Renal Allograft Rejection.
Rekers NV et al.
Transplantation, 2017
Pharmacogenetics and induction/consolidation therapy toxicities in acute lymphoblastic leukemia patients treated with AIEOP-BFM ALL 2000 protocol.
Franca R et al.
The Pharmacogenomics Journal, 2017
Glucocorticoid Receptor Gene Variants and Neonatal Outcome in Very-Low-Birth-Weight Preterm Infants.
Schreiner C et al.
Neonatology, 2017
Molecular Guided Therapy Provides Sustained Clinical Response in Refractory Choroid Plexus Carcinoma.
Cornelius A et al.
Frontiers in Pharmacology, 2017
Glucocorticoid receptor variants in childhood attention-deficit/hyperactivity disorder and comorbid psychiatric disorders.
Schote AB et al.
Psychiatry Research, 2016
Healthy glucocorticoid receptor N363S carriers dysregulate gene expression associated with metabolic syndrome.
Jewell CM et al.
American Journal of Physiology. Endocrinology and Metabolism, 2016
Influence of BclI C/G (rs41423247) on hippocampal shape and white matter integrity of the parahippocampal cingulum in major depressive disorder.
Won E et al.
Psychoneuroendocrinology, 2016
The role of the glucocorticoid receptor gene (NR3C1) for the processing of aversive stimuli.
Schneider KK et al.
Neuroscience Research, 2016
The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation.
Li-Tempel T et al.
Clinical Epigenetics, 2016
Analysis of BCLI, N363S and ER22/23EK Polymorphisms of the Glucocorticoid Receptor Gene in Adrenal Incidentalomas.
Reimondo G et al.
Plos One, 2016
Association of the glucocorticoid receptor D641V variant with steroid-resistant asthma: a case-control study.
Zhao F et al.
Pharmacogenetics and Genomics, 2015
Antenatal glucocorticoid treatment and polymorphisms of the glucocorticoid and mineralocorticoid receptors are associated with IQ and behavior in young adults born very preterm.
van der Voorn B et al.
The Journal of Clinical Endocrinology and Metabolism, 2015
Glucocorticoid receptor polymorphisms and haplotypes and their expression in health and disease.
Koper JW et al.
Steroids, 2014
Structural and energetic analyses of SNPs in drug targets and implications for drug therapy.
Sun HY et al.
Journal of Chemical Information and Modeling, 2013
Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease.
Cooper DN et al.
Human Genetics, 2013
Exploring the molecular mechanisms of glucocorticoid receptor action from sensitivity to resistance.
Ramamoorthy S et al.
Endocrine Development, 2013
Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder.
Sinclair D et al.
Bmc Psychiatry, 2012
Glucocorticoid receptor 1B and 1C mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by GR gene variants.
Sinclair D et al.
Plos One, 2012
Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder.
Szczepankiewicz A et al.
Journal of Affective Disorders, 2011
A genetic predisposition score for muscular endophenotypes predicts the increase in aerobic power after training: the CAREGENE study.
Thomaes T et al.
Bmc Genetics, 2011
Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome.
Valkenburg O et al.
Human Reproduction (oxford, England), 2011
Abdominal fat accumulation in adults born preterm exposed antenatally to maternal glucocorticoid treatment is dependent on glucocorticoid receptor gene variation.
Finken MJ et al.
The Journal of Clinical Endocrinology and Metabolism, 2011
Transcriptional control of the human glucocorticoid receptor: identification and analysis of alternative promoter regions.
Cao-Lei L et al.
Human Genetics, 2011
Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing.
Wang W et al.
Nucleic Acids Research, 2011
Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.
Mwinyi J et al.
World Journal of Gastroenterology, 2010
Polymorphisms in glucocorticoid receptor gene and the outcome of childhood acute lymphoblastic leukemia (ALL).
Labuda M et al.
Leukemia Research, 2010
Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study.
Geelhoed MJ et al.
Bmc Medical Genetics, 2010
Glucocorticoid receptor polymorphisms in major depression.
Claes S
Annals of the New York Academy of Sciences, 2009
IL-10 and TNF-alpha promoter haplotypes are associated with childhood Crohn's disease location.
Sanchez R et al.
World Journal of Gastroenterology, 2009
Human glucocorticoid receptor alpha gene (NR3C1) pharmacogenomics: gene resequencing and functional genomics.
Niu N et al.
The Journal of Clinical Endocrinology and Metabolism, 2009
Characterization of a glucocorticoid receptor gene (GR, NR3C1) promoter polymorphism reveals functionality and extends a haplotype with putative clinical relevance.
Kumsta R et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2009
Functional glucocorticoid receptor gene variants do not underlie the high variability of 17-hydroxyprogesterone screening values in healthy newborns.
Schreiner F et al.
European Journal of Endocrinology, 2009