Varaico: Literature-Extracted Genetic Variants

NR3C1

1,293 papers

RefSeq Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activ...

Pfam Domains

GCRaa 26–401UCSCGlucocorticoid receptor

zf-C4aa 419–488UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 549–741UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

nuclear receptor subfamily 3 group C member 1

HGNC Previous Symbol

GRL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

65 papers

NM_000176.3

p.R23K

c.68G>A

Surrounding Variants

1 paper

NM_000176.3

p.R23T

c.68G>C

2 papers

NM_000176.3

p.E22_R23delins

c.66_68delinsAAA

1 paper

NM_000176.3

p.R23W

c.67A>T

1 paper

NM_000176.3

p.E22D

c.66G>T

1 paper

NM_000176.3

p.E22D

c.66G>C

6 papers

NM_000176.3

p.E22E

c.66G>A

5 papers

NM_000176.3

p.G24E

c.71G>A

1 paper

NM_000176.3

p.E22G

c.65A>G

1 paper

NM_000176.3

p.E22A

c.65A>C

1 paper

NM_000176.3

p.G24G

c.72A>G

2 papers

NM_000176.3

p.D25N

c.73G>A

1 paper

NM_000176.3

p.D25insFs

c.74_75insG