Varaico: Literature-Extracted Genetic Variants

Gene:NTRK2
Variant:p.G639R
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NTRK2

NM_006180.6:p.G639R

Associated Papers

Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion.

Keane S et al.

Npj Precision Oncology, 2025

Circulating tumor DNA profiling for non-invasive genomic analysis in Indian lung cancer patients: A real-world experience.

Jha P et al.

The Journal of Liquid Biopsy, 2025

40503459 (PubMed )
Supplement: mmc1.xlsx › Supplementary_Table_S2

BPI-28592 as a novel second generation inhibitor for NTRK fusion tumors.

Sheng J et al.

Npj Precision Oncology, 2024

Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents.

Roa P et al.

British Journal of Cancer, 2024

Prevalence and clinico-genomic characteristics of patients with TRK fusion cancer in China.

Xu Y et al.

Npj Precision Oncology, 2023

JND4135, a New Type II TRK Inhibitor, Overcomes TRK xDFG and Other Mutation Resistance In Vitro and In Vivo.

Wang J et al.

Molecules (basel, Switzerland), 2022

Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant Mutations.

Murray BW et al.

Molecular Cancer Therapeutics, 2021

What hides behind the MASC: clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC).

Drilon A et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2016

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