Associated Papers
Role of PRKCZ non-synonymous genetic variants in breast cancer development.
Mustafa A et al.
Cancer Cell International, 2025
The chordoid glioma PRKCA D463H mutation is a kinase inactive, gain-of-function allele that induces early-onset chondrosarcoma in mice.
Calleja V et al.
Science Signaling, 2025
Discriminating activating, deactivating and resistance variants in protein kinases.
Singh G et al.
Genome Medicine, 2025
ROBIN: A unified nanopore-based assay integrating intraoperative methylome classification and next-day comprehensive profiling for ultra-rapid tumor diagnosis.
Deacon S et al.
Neuro-oncology, 2025
A Catalytically Inactive Protein Kinase C alpha Mutation Drives Chordoid Glioma by Pathway Rewiring.
Bellamy C et al.
Biorxiv : the Preprint Server for Biology, 2025
Molecular markers for pediatric low-grade glioma.
Levine AB et al.
Child's Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery, 2024
Rare Neuronal, Glial and Glioneuronal Tumours in Adults.
Crainic N et al.
Cancers, 2023
Droplet digital PCR-based analyses for robust, rapid, and sensitive molecular diagnostics of gliomas.
Wolter M et al.
Acta Neuropathologica Communications, 2022
[Chordoid glioma: a clinicopathological study].
Wang LM et al.
Zhonghua Bing Li Xue Za Zhi = Chinese Journal of Pathology, 2021
The complexities of PKCα signaling in cancer.
Black AR et al.
Advances in Biological Regulation, 2021
Occurrence of Chordoid Glioma With Sodium Ion Metabolism Disorder 5 Years After Meningioma Surgery and Whole-Exome Sequencing: A Case Report and Literature Review.
Zhang M et al.
Frontiers in Genetics, 2021
PRKCA D463H Mutation in Chordoid Glioma of the Third Ventricle: A Cohort of 16 Cases, Including Two Cases Harboring BRAFV600E Mutation.
Yao K et al.
Journal of Neuropathology and Experimental Neurology, 2020
A review of recently described genetic alterations in central nervous system tumors.
Lucas CG et al.
Human Pathology, 2020
Estimating the Frequency of Single Point Driver Mutations across Common Solid Tumours.
Darbyshire M et al.
Scientific Reports, 2019
Molecular classification of adult gliomas: recent advances and future perspectives.
Barritault M et al.
Current Opinion in Oncology, 2018
A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas.
Rosenberg S et al.
Nature Communications, 2018
A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.
Goode B et al.
Nature Communications, 2018
Cytologic alterations in hereditary metabolic disorders. I. The effects of galactose on galactosemic fibroblasts in vitro.
Miller LR et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 1968