Varaico: Literature-Extracted Genetic Variants

Gene:PTPN11
Variant:p.G13R
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PTPN11

NM_002834.5:p.G13R

Associated Papers

Deep mutational scanning of a multi-domain signaling protein reveals mechanisms of regulation and pathogenicity.

Jiang Z et al.

Biorxiv : the Preprint Server for Biology, 2024

39091798 (PubMed )
Supplement: media-3.xlsx › SHP2-FL_cSrc-KD_column

Colchicine prevents accelerated atherosclerosis in TET2-mutant clonal haematopoiesis.

Zuriaga MA et al.

European Heart Journal, 2024

39212933 (PubMed )
Supplement: ehae546_supplementary_data.pdf

Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk.

Yu Z et al.

The Journal of Clinical Investigation, 2023

37498674 (PubMed )
Supplement: jci-133-168597-s140.pdf

Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function.

Ali S et al.

Frontiers in Chemistry, 2023

Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia.

Kaburagi T et al.

Haematologica, 2022

Clinical Implication of Concordant or Discordant Genomic Profiling between Primary and Matched Metastatic Tissues in Patients with Colorectal Cancer.

Choi JY et al.

Cancer Research and Treatment, 2020

PTPN11, RAS and FLT3 mutations in childhood acute lymphoblastic leukemia.

Yamamoto T et al.

Leukemia Research, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."