Varaico: Literature-Extracted Genetic Variants

Gene:RPS6KB1
Variant:p.T412A
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RPS6KB1

NM_003161.4:p.T412A

Associated Papers

Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo.

Lizcano JM et al.

The Journal of Biological Chemistry, 2002

Loss of hydrophobic motif and activation loop phosphorylation is a consequence and not the mechanism of S6 kinase 1 inhibition by rapamycin.

Beigh MA et al.

Journal of Biological Regulators and Homeostatic Agents, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."