Varaico: Literature-Extracted Genetic Variants

Gene:RPS6KB1
Variant:p.T412A

RPS6KB1

318 papers

RefSeq Summary

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, c...

Pfam Domains

Pkinaseaa 91–352UCSCProtein kinase domain
Pkinase_Caa 373–413UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase B1

HGNC Previous Symbol

STK14A

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_003161.4
p.T412A
c.1234A>G
Surrounding Variants
1 paper
NM_003161.4
p.T412S
c.1234A>T
1 paper
NM_001272042.2
p.P393A
c.1177C>G
1 paper
NM_003161.4
p.E429insFs
c.1285_1286insC
4 papers
NM_003161.4
p.P445S
c.1333C>T
1 paper
NM_003161.4
p.P448S
c.1342C>T
1 paper
NM_003161.4
p.W457L
c.1370G>T
1 paper
NM_003161.4
p.R459*
c.1375A>T
1 paper
NM_003161.4
p.R459I
c.1376G>T
1 paper
NM_003161.4
p.S464R
c.1392C>A
1 paper
NM_003161.4
p.E473Q
c.1417G>C
1 paper
NM_003161.4
p.N502_S503insYA
c.1504_1508ins6
1 paper
NM_003161.4
p.G504R
c.1510G>A
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