Varaico: Literature-Extracted Genetic Variants

Gene:TLR4
Variant:p.D299G
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TLR4

NM_138554.5:p.D299G

Associated Papers

The association between toll-like receptor gene polymorphism and Helicobacter pylori infection risk: A systematic review and meta-analysis.

Xu Z et al.

Medicine, 2026

From Bench to Bedside: Personalized Genomics in the Diagnosis and Treatment of Osteomyelitis.

Hoveidaei AH et al.

Antibiotics (basel, Switzerland), 2026

The Impact of TLR4 rs41426344 Polymorphism on Ankylosing Spondylitis Disease Activity: A Study in Turkish Patients.

Kirkik D et al.

International Journal of Immunogenetics, 2026

Protective Association of TLR6 rs5743810 with Pulmonary Tuberculosis in the Population of JAMMU Region.

Sharma S et al.

Indian Journal of Microbiology, 2026

Host genetic factors modulating dengue virus: a systematic review of TLR polymorphisms.

Candrasari DS et al.

Bmc Infectious Diseases, 2026

Exploratory Analysis of TLR2, TLR4, Interleukin 6 and Interleukin 10 Gene Polymorphisms in Relation to Clinical Early-Onset Sepsis in Preterm Neonates: A Single-Center Study.

Baizat M et al.

Life (basel, Switzerland), 2026

Polymorphisms in TLR4 and IL6 and their association with obesity and insulin resistance in a Venezuelan population.

Hernández Osorio S et al.

Endocrinologia, Diabetes Y Nutricion, 2026

Genetic polymorphisms and diabetic foot ulcer susceptibility: a systematic review and meta-analysis of Indian populations.

Kumar YS et al.

Journal of Diabetes and Metabolic Disorders, 2025

TLR4 rs4986790 and TLR9 rs5743836 Polymorphisms and Their Association With Clinical Outcomes of Leishmania infantum Infection in Tunisia.

Chargui N et al.

Cureus, 2025

Association of TLR-4 and TLR-9 Polymorphisms with HPV Infection and Cervical Dysplasia in Hispanic Women.

Mendez K et al.

Cancers, 2025

Toll-like receptor 3 (TLR 3) polymorphisms predisposition to schizophrenia and bipolar disorder.

Aflouk Y et al.

Molecular Biology Reports, 2025

Increased expression of Toll-like receptors and associated alarmins in temporal arteries of patients with giant cell arteritis.

Seidlberger S et al.

Molecular Medicine (cambridge, Mass.), 2025

The Role of TLR2/TLR4 Receptors in Host Genetic Susceptibility to Recurrent Vulvovaginitis.

Routsias J et al.

Journal of Fungi (basel, Switzerland), 2025

Genetic markers at the crossroads: toll-like receptor polymorphisms and Plasmodium vivax malaria parasitological aspects from the Brazil-French Guiana border.

Cerilo-Filho M et al.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2025

Genetic Testing in Periodontitis: A Narrative Review on Current Applications, Limitations, and Future Perspectives.

Modafferi C et al.

Genes, 2025

Association of SLC22A4 and TNF-α gene polymorphism with susceptibility to inflammatory bowel disease among patients in the Eastern Province of Saudi Arabia.

AlQahtani SM et al.

Arab Journal of Gastroenterology : the Official Publication of the Pan-arab Association of Gastroenterology, 2025

Bilateral Sequential Herpes Simplex Type 2 Panophthalmitis in an Adult with a Toll-Like Receptor 4 Mutation.

Wong SW et al.

Ocular Immunology and Inflammation, 2025

Interaction between toll-like receptor 4 polymorphism and abdominal obesity on ovarian cancer risk in Chinese women.

Zhu J et al.

Bmc Women's Health, 2025

Exploratory Study on Genetic Variants Related to Hydatidosis Susceptibility and Albendazole Pharmacogenetics in the Cusco Region in Peru.

Jaramillo-Valverde L et al.

Frontiers in Bioscience (scholar Edition), 2025

TLR4 rs2149356 Polymorphism in Periodontitis and End-Stage Renal Disease: An Exploratory Analysis in Egyptian Patients.

Abou-Bakr A et al.

Cells, 2025

TLR-4 genetic variants as predictive biomarkers for susceptibility and clinical outcomes in triple-negative breast cancer: A case control study.

El-Ghali RM et al.

Gene, 2025

Assessment of rs1205 and rs1130864 Polymorphisms of C-Reactive Protein Gene (CRP) and Serum CRP Levels in Immune Thrombocytopenia: A Case-Control Study.

Sarbazjoda E et al.

Health Science Reports, 2025

Correction: Role of TLR4 Asp299Gly and Thr399Ile Gene Polymorphisms as a Risk Factor in Human Cytomegalovirus Positive Pregnant Women.

Fatima T et al.

Reproductive Sciences (thousand Oaks, Calif.), 2025

Genetic Variations in TLR2 and TLR4 Genes and Their Association With COVID-19 Severity and Inflammatory Markers in the Moroccan Population.

Noureddine R et al.

International Journal of Immunogenetics, 2025

Impact of Sociodemographic, Clinical, and Genetic Factors and Fusobacterium nucleatum on Premature Birth Outcomes in Women from Kazakhstan: A Case-Control Study.

Zhurabekova G et al.

Iranian Journal of Medical Sciences, 2025

TLR4 Asp299Gly SNP (rs4986790) Protects from Periodontal Inflammatory Destruction by Altering TLR4 Susceptibility to LPS Stimulation.

Cavalla F et al.

Biology, 2025

Genetic and immunological regulation of gut Microbiota: The Roles of TLRs, CLRs, and key proteins in microbial homeostasis and disease.

Ayoub M et al.

Gene, 2025

Role of TLR4 Asp299Gly and Thr399Ile Gene Polymorphisms as a Risk Factor in Human Cytomegalovirus Positive Pregnant Women.

Fatima T et al.

Reproductive Sciences (thousand Oaks, Calif.), 2025

TLR8 and TLR9 gene polymorphisms and the risk of high-grade serous ovarian cancer.

Haręża DA et al.

International Journal of Biological Macromolecules, 2025

Gene variants, oxidative stress and inflammation in Colombian populations

Banguera DN et al.

Biomedica : Revista Del Instituto Nacional De Salud, 2025

Genetic Predisposition of TLR 1 and TLR 6 Polymorphisms to Schizophrenia Onset and Prediction of Treatment Response.

Aflouk Y et al.

Biochemical Genetics, 2025

Host genetic variation governs PCV2 susceptibility through CXCL13 and ELK1-mediated immune regulation.

Liu G et al.

International Journal of Biological Macromolecules, 2025

Host Genetic Factors in Q Fever Susceptibility.

Robaina Bordón JM et al.

Pathogens (basel, Switzerland), 2025

Metabolic Characteristics and Cytokine Gene Polymorphisms as Potential Risk Factors for a Higher Liver Fibrosis Stage in MASLD Patients: A Hospital-Based Study.

Iancu M et al.

International Journal of Molecular Sciences, 2025

Polymorphisms Involved in Insulin Resistance and Metabolic Inflammation: Influence of Nutrients and Dietary Interventions.

Duarte GBS et al.

Metabolites, 2025

Structural insights into ACE2 interactions and immune activation of SARS-CoV-2 and its variants: an in-silico study.

Yousefbeigi S et al.

Journal of Biomolecular Structure & Dynamics, 2025

Features of toll-like receptor genes (TLR-2, TLR-3, TLR-4 and TLR-6) polymorphism in open-angle glaucoma patients.

Shevchenko AV et al.

Vavilovskii Zhurnal Genetiki I Selektsii, 2025

TLR4 and TNF-α single nucleotide polymorphisms in patients with brucellosis: Association with infection complications.

Giannitsioti E et al.

European Journal of Internal Medicine, 2025

Associations between Toll-like receptor 4 Asp299Gly polymorphism and susceptibility to intracranial aneurysm among male and female patients within the North Indian population.

Singh A et al.

Neurological Research, 2025

Role of genetic variants and DNA methylation of lipid metabolism-related genes in metabolic dysfunction-associated steatotic liver disease.

Wang JJ et al.

Frontiers in Physiology, 2025

40166716 (PubMed )
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TLR4/MyD88 expression patterns and novel genetic variants: association with aggressive clinicopathological features in colorectal cancer.

Dang TT et al.

Frontiers in Oncology, 2025

The impact of TLR4 gene polymorphisms on the risk of developing diabetic foot syndrome in case of type 2 diabetes mellitus.

Bilyayeva O et al.

Wiadomosci Lekarskie (warsaw, Poland : 1960), 2025

Association of toll-like receptor 4 gene (Thr399Ile) polymorphism with type II diabetes mellitus patients.

Mohammed AJ et al.

Wiadomosci Lekarskie (warsaw, Poland : 1960), 2025

Identification of novel amino acid variants in the Han Chinese population that impair toll-like receptor 4 signaling and confer hyporesponsiveness to lipopolysaccharide.

Zhou B et al.

Frontiers in Immunology, 2025

TLR4 rs11536889 and rs1927914 SNPs are Associated with Ischemic Stroke Risk in a Southern Chinese Han Population.

Liu Y et al.

International Journal of General Medicine, 2025

Vitiligo: From mechanisms of disease to treatable pathways.

Pathak GN et al.

Skin Health and Disease, 2024

Investigation of TLR4 Polymorphism in Children with Vesicoureteral Reflux and Renal Scarring.

Sav NM et al.

Balkan Journal of Medical Genetics : Bjmg, 2024

Single Nucleotide Polymorphisms on Toll-like Receptor-4 and the Risk of Developing Skin Cancer.

Yusuf N et al.

International Journal of Molecular Sciences, 2024

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."