Associated Papers
SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis.
Chouhan S et al.
Nature Communications, 2024
Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance.
Sridaran D et al.
Nature Communications, 2022
The brain-specific splice variant of the CDC42 GTPase works together with the kinase ACK to downregulate the EGF receptor in promoting neurogenesis.
Endo M et al.
The Journal of Biological Chemistry, 2022
The two splice variant forms of Cdc42 exert distinct and essential functions in neurogenesis.
Endo M et al.
The Journal of Biological Chemistry, 2020
Cortactin is a substrate of activated Cdc42-associated kinase 1 (ACK1) during ligand-induced epidermal growth factor receptor downregulation.
Kelley LC et al.
Plos One, 2012
The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors.
Teo M et al.
The Journal of Biological Chemistry, 2001
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