Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.T304I
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TP53

NM_000546.6:p.T304I

Associated Papers

TP53 mutation heterogeneity reveals distinct prognoses in mantle cell lymphoma.

Liu S et al.

Annals of Hematology, 2026

41559357 (PubMed )
Supplement: 277_2026_6771_MOESM2_ESM.xlsx › TableS3

Towards Personalized Precision Oncology: A Feasibility Study of NGS-Based Variant Analysis of FFPE CRC Samples in a Chilean Public Health System Laboratory.

Durán-Jara E et al.

Current Issues in Molecular Biology, 2025

40864753 (PubMed )
Supplement: cimb-47-00599-s001.zip › Supplementary_Table_S4_-_VAF_and_actionability.pdf

Scalable approaches for generating, validating and incorporating data from high-throughput functional assays to improve clinical variant classification.

Padigepati SR et al.

Human Genetics, 2024

39085601 (PubMed )
Supplement: 439_2024_2691_MOESM2_ESM.xlsx › TP53

Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.

Tam B et al.

Briefings in Bioinformatics, 2024

39140857 (PubMed )
Supplement: table_s1_bbae400.xlsx › Sheet1

TP53 variants in p53 signatures and the clonality of STICs in RRSO samples.

Akahane T et al.

Journal of Gynecologic Oncology, 2022

35557033 (PubMed )
Supplement: jgo-33-e50-s002.xls › jgo-33-e50-s002

TP53 Mutation Analysis in Gastric Cancer and Clinical Outcomes of Patients with Metastatic Disease Treated with Ramucirumab/Paclitaxel or Standard Chemotherapy.

Graziano F et al.

Cancers, 2020

Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival.

Yokouchi H et al.

Heliyon, 2020

Advances in sarcoma gene mutations and therapeutic targets.

Gao P et al.

Cancer Treatment Reviews, 2018

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Holehouse AS et al.

Plos One, 2015

26659599 (PubMed )
Supplement: pone.0144692.s002.xlsx › suppTable_2.txt

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

Holstege H et al.

Cancer Research, 2009

Prognostic significance of p53 gene mutations and protein overexpression in localized gastrointestinal stromal tumours.

Ryu MH et al.

Histopathology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."