Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.G245del1
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TP53

NM_000546.6:p.G245del1

Associated Papers

Identification of high-risk signatures and therapeutic targets through molecular characterization and immune profiling of TP53-mutant breast cancer.

Paulino PJIV et al.

Journal, Genetic Engineering & Biotechnology, 2025

41386839 (PubMed )
Supplement: mmc5.xlsx › Table_S3

Impact of TP53 Genomic Alterations in Large B-Cell Lymphoma Treated With CD19-Chimeric Antigen Receptor T-Cell Therapy.

Shouval R et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2022

34860572 (PubMed )
Supplement: DS_JCO.21.02143.xlsx › Table_S3

Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Cobain EF et al.

Jama Oncology, 2021

33630025 (PubMed )
Supplement: jamaoncol-e207987-s004.xlsx › Table

Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53-associated features.

Benor G et al.

Molecular Oncology, 2020

32484602 (PubMed )
Supplement: MOL2-14-1640-s002.pdf

Only missense mutations affecting the DNA binding domain of p53 influence outcomes in patients with breast carcinoma.

Végran F et al.

Plos One, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."