Associated Papers
TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup.
Fischer NW et al.
Nature Communications, 2025
41022739 (PubMed )
Supplement: 41467_2025_63528_MOESM7_ESM.xlsx › Sheet1
Unraveling the unique amyloid-like aggregation behavior of the tumor suppressor p53 mutants in human cancers.
Manav N et al.
International Journal of Biological Macromolecules, 2025
Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.
Funk JS et al.
Nature Genetics, 2025
39774325 (PubMed )
Supplement: 41588_2024_2039_MOESM5_ESM.xlsx › SuppFig6
Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.
Tam B et al.
Briefings in Bioinformatics, 2024
39140857 (PubMed )
Supplement: table_s1_bbae400.xlsx › Sheet1
Understanding the prion-like behavior of mutant p53 proteins in triple-negative breast cancer pathogenesis: The current therapeutic strategies and future directions.
Naeimzadeh Y et al.
Heliyon, 2024
p53 amyloid aggregation in cancer: function, mechanism, and therapy.
Li J et al.
Experimental Hematology & Oncology, 2022
Ultrasensitive profiling of UV-induced mutations identifies thousands of subclinical facial tumors in tuberous sclerosis complex.
Klonowska K et al.
The Journal of Clinical Investigation, 2022
35358092 (PubMed )
Supplement: jci-132-155858-s188.xlsx › Supplemental_Table_5.1.
TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.
Ben-Cohen G et al.
Briefings in Bioinformatics, 2022
35043155 (PubMed )
Supplement: supplementary_table_s1_bbab524.xlsx › S1B._Negative_Set
Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?
Costa DC et al.
Cold Spring Harbor Perspectives in Biology, 2016
Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.
de Oliveira GA et al.
Frontiers in Oncology, 2015
Genomic instability at the 13q31 locus and somatic mtDNA mutation in the D-loop site correlate with tumor aggressiveness in sporadic Brazilian breast cancer cases.
Santos GC et al.
Clinics (sao Paulo, Brazil), 2012
Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors.
Levy CB et al.
The International Journal of Biochemistry & Cell Biology, 2011
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