Associated Papers
TP53 mutation heterogeneity reveals distinct prognoses in mantle cell lymphoma.
Liu S et al.
Annals of Hematology, 2026
Distinct functional heterogeneity of TP53 R175 mutations in platinum-resistant ovarian cancer: unveiling molecular mechanisms and therapeutic targets.
Liu Y et al.
Cell Death & Disease, 2025
TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup.
Fischer NW et al.
Nature Communications, 2025
Circulating tumor DNA profiling for non-invasive genomic analysis in Indian lung cancer patients: A real-world experience.
Jha P et al.
The Journal of Liquid Biopsy, 2025
Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.
Funk JS et al.
Nature Genetics, 2025
Redefining aberrant P53 expression of gastric cancer and its distinct clinical significance among molecular-histologic subtypes.
Huang SC et al.
Asian Journal of Surgery, 2024
Comprehensive classification of TP53 somatic missense variants based on their impact on p53 structural stability.
Tam B et al.
Briefings in Bioinformatics, 2024
Mutations in the TP53, VEGFA, and CTH Genes as Key Molecular Markers for the Diagnosis of Glioblastoma.
Khalil SS et al.
Cureus, 2024
Molecular Divergence upon EGFR-TKI Resistance Could Be Dependent on the Exon Location of the Original EGFR-Sensitizing Mutation.
Serna-Blasco R et al.
Cancers, 2022
Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.
Doffe F et al.
Cell Death and Differentiation, 2021
Mutant p53 in cancer therapy-the barrier or the path.
Zhou X et al.
Journal of Molecular Cell Biology, 2019
Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces.
Engin HB et al.
Plos One, 2016
Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions.
Brannon AR et al.
Genome Biology, 2014
Small molecule compounds targeting the p53 pathway: are we finally making progress?
Yu X et al.
Apoptosis : an International Journal on Programmed Cell Death, 2014
IDH1/IDH2 but not TP53 mutations predict prognosis in Bulgarian glioblastoma patients.
Stancheva G et al.
Biomed Research International, 2014
COLD-PCR enrichment of rare cancer mutations prior to targeted amplicon resequencing.
Milbury CA et al.
Clinical Chemistry, 2012
Predicting the functional impact of protein mutations: application to cancer genomics.
Reva B et al.
Nucleic Acids Research, 2011
The role of mutant p53 in human cancer.
Goh AM et al.
The Journal of Pathology, 2011
Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events.
Chen Z et al.
Plos One, 2008
The UMD TP53 database and website: update and revisions.
Hamroun D et al.
Human Mutation, 2006