Varaico: Literature-Extracted Genetic Variants

Gene:TP53
Variant:p.L25L
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TP53

NM_000546.6:p.L25L

Associated Papers

TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact.

Canson DM et al.

Npj Genomic Medicine, 2025

40341019 (PubMed )
Supplement: 41525_2025_498_MOESM2_ESM.xlsx › Data_S2

Oncogenic composite mutations can be predicted by co-mutations and their chromosomal location.

Küçükosmanoglu A et al.

Molecular Oncology, 2024

38757376 (PubMed )
Supplement: MOL2-18-2407-s001.xlsx › 1B_Cases_composite_mutations

A novel molecular classification system based on the molecular feature score identifies patients sensitive to immune therapy and target therapy.

Li Y et al.

Frontiers in Immunology, 2024

39660131 (PubMed )
Supplement: Table1.xlsx › S7.DrugPredictions

A gene mutation-based risk model for prognostic prediction in liver metastases.

Yu B et al.

Bmc Genomics, 2023

37633919 (PubMed )
Supplement: 12864_2023_9595_MOESM2_ESM.xlsx › Table_S3

ZNF498 promotes hepatocellular carcinogenesis by suppressing p53-mediated apoptosis and ferroptosis via the attenuation of p53 Ser46 phosphorylation.

Zhang X et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2022

35227287 (PubMed )
Supplement: 13046_2022_2288_MOESM4_ESM.xlsx › Table_S3_ZNF498_mRNA_level_and_

Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer.

Ciani Y et al.

Cell Systems, 2022

34731645 (PubMed )
Supplement: mmc2.xlsx › Study_Sample_Info_File

Genomic characterization of rare molecular subclasses of hepatocellular carcinoma.

Damrauer JS et al.

Communications Biology, 2021

34608257 (PubMed )
Supplement: 42003_2021_2674_MOESM3_ESM.xlsx › Supplementary_Data_1

Tumor hepatitis B virus RNA identifies a clinically and molecularly distinct subset of hepatocellular carcinoma.

Lim HC et al.

Plos Computational Biology, 2021

33561166 (PubMed )
Supplement: pcbi.1008699.s006.xlsx › TCGA_Tumors

Somatic Mutation Profiles Revealed by Next Generation Sequencing (NGS) in 39 Chinese Hepatocellular Carcinoma Patients.

Ke L et al.

Frontiers in Molecular Biosciences, 2021

35118119 (PubMed )
Supplement: Table6.xlsx › Sheet1

Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer.

Kwon SM et al.

Scientific Reports, 2019

31729408 (PubMed )
Supplement: 41598_2019_52578_MOESM2_ESM.pdf

Differences in somatic mutation landscape of hepatocellular carcinoma in Asian American and European American populations.

Yao S et al.

Oncotarget, 2016

27246981 (PubMed )
Supplement: oncotarget-07-40491-s002.xlsx › Table_S2
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."