Associated Papers
Novel germline and somatic variants in familial and sporadic meningioma genes.
Bencheikh BOA et al.
Npj Genomic Medicine, 2025
A comprehensive benchmark for multiple highly efficient base editors with broad targeting scope.
Wang X et al.
Biorxiv : the Preprint Server for Biology, 2025
A Cohort Study of CNS Tumors in Multiple Endocrine Neoplasia Type 1.
Graillon T et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024
Normal meninges harbor oncogenic somatic mutations in meningioma-driver genes.
Boetto J et al.
Acta Neuropathologica, 2023
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
Youngblood MW et al.
Nature Communications, 2023
TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development.
Tsitsikov EN et al.
Iscience, 2023
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.
Mishra-Gorur K et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023
Genomic profiling of sporadic multiple meningiomas.
Erson-Omay EZ et al.
Bmc Medical Genomics, 2022
Prognostic impact of genetic alterations and methylation classes in meningioma.
Berghoff AS et al.
Brain Pathology (zurich, Switzerland), 2022
Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development.
Najm P et al.
Cancer Research, 2021
Sporadic multiple meningiomas harbor distinct driver mutations.
Juratli TA et al.
Acta Neuropathologica Communications, 2021
Molecular characterization of diffuse malignant peritoneal mesothelioma.
Hung YP et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2020
Phenotypic spectrum and transcriptomic profile associated with germline variants in TRAF7.
Castilla-Vallmanya L et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2020
Well-Differentiated Papillary Mesothelioma of the Peritoneum Is Genetically Distinct from Malignant Mesothelioma.
Shrestha R et al.
Cancers, 2020
Mutation Status and Epithelial Differentiation Stratify Recurrence Risk in Chordoid Meningioma-A Multicenter Study with High Prognostic Relevance.
Georgescu MM et al.
Cancers, 2020
Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42.
Stevers M et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2019
Whole exome sequencing of multiple meningiomas with varying histopathological presentation in one patient revealed distinctive somatic mutation burden and independent clonal origins.
Sheng HS et al.
Cancer Management and Research, 2019
Genetic Alterations of TRAF Proteins in Human Cancers.
Zhu S et al.
Frontiers in Immunology, 2018
Frequent AKT1E17K mutations in skull base meningiomas are associated with mTOR and ERK1/2 activation and reduced time to tumor recurrence.
Yesilöz Ü et al.
Neuro-oncology, 2017
Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.
Clark VE et al.
Science (new York, N.y.), 2013
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.
Reuss DE et al.
Acta Neuropathologica, 2013