Varaico: Literature-Extracted Genetic Variants

TRAF7

256 papers

RefSeq Summary

Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-...

Pfam Domains

zf-RING_UBOXaa 131–166UCSCRING-type zinc-finger

WD40aa 386–424UCSCWD domain, G-beta repeat

WD40aa 429–465UCSCWD domain, G-beta repeat

WD40aa 469–504UCSCWD domain, G-beta repeat

WD40aa 589–629UCSCWD domain, G-beta repeat

WD40aa 633–669UCSCWD domain, G-beta repeat

Gene Aliases

HGNC Name

TNF receptor associated factor 7

HGNC Previous Symbol

RFWD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

22 papers

NM_032271.3

p.N520S

c.1559A>G

Surrounding Variants

1 paper

NM_032271.3

p.N520T

c.1559A>C

3 papers

NM_032271.3

p.N520H

c.1558A>C

1 paper

NM_032271.3

p.N520D

c.1558A>G

2 papers

NM_032271.3

p.H521N

c.1561C>A

9 papers

NM_032271.3

p.H521R

c.1562A>G

6 papers

NM_032271.3

p.L519P

c.1556T>C

2 papers

NM_032271.3

p.L519R

c.1556T>G

3 papers

NM_032271.3

p.L519F

c.1555C>T

1 paper

NM_032271.3

p.W522R

c.1564T>A

1 paper

NM_032271.3

p.W522R

c.1564T>C

10 papers

NM_032271.3

p.R524W

c.1570C>T

1 paper

NM_032271.3

p.L516F

c.1546C>T